대표 논문
◆Lee, S.*, Song H.R.*, Park, K., Lee, M., Lee, A.H., Roh, S.M., Park, Y., Kim, H.J., Kwon, Y., Yang, S.H.# and Kim, J.#. Quantitative analysis of PACAP-38 and amyloid beta composition using a dual reaction in reduced graphene oxide biosensor to verify the neuroprotective role of PACAP-38. Sensors and Actuators: B. Chemical. (2022) 361, 131727
◆Jang, D.I., Shin, H.Y., Lee, A.H., Song, H.R., Park, J.W., Kang, T.B., Lee, S.R.# and Yang, S.H.# The role of tumor necrosis factor alpha (TNF-α) in autoimmune disease and current TNF-α inhibitors in therapeutics. Int J Mol Sci. (2021), 22(5), 2719
◆Lee, J.H., Ahn, N.H., Choi, S.B., Kwon, Y. and Yang, S.H. Natural products targeting Amyloid beta in Alzheimer's disease. Int J Mol Sci. (2021), 22(5), 2341.
◆Lee, A.H., Shin, H.Y., Park, J.H., Koo, S.Y., Kim, S.M., and Yang, S.H. Fucoxanthin from microalgae Phaeodactylum tricornutum inhibits pro-inflammatory cytokines by regulating both NF-κB and NLRP3 inflammasome activation. Sci Rep. (2021), 11, 543
◆Kwon, Y.*, Shin, J.*, Nam, K., An, J.S., Yang, S.H., Hong, S.H., Bae, M., Moon, K., Cho, Y., Woo, J., Park, K., Kim, K., Shin, J., Kim, B.Y., Kim, Y., and Oh, D.C. Rhizolutin, a novel 7/10/6-tricyclic dilactone, dissociates misfolded protein aggregates and reduces apoptosis/inflammation associated with Alzheimer’s disease. Angewandte Chemie. (2020), 59(51), 22994-22998.
◆Lee, JC., Kim, H.Y., Lee, S., Shin, J., Kim, V.H., Kim, K, Baek, S., Lee, D., Jeon, H., Kimm DW., Yang, S.H., Han, G., Park, KW., Choi., J., Park, J., Moss, J., Janda K., and Kim, Y. Discovery of chemicals to clear or indicate amyloid aggregates by targeting memory-impairing anti-parallel Aβ dimers. Angewandte Chemie. (2020), 59(28), 11491-11500.
◆Kang, T.B., Jeong, J.S., Yang, S.H., Kovalenko, A., and Wallach, D. Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3. Cell Death Differ, (2018), 25(6), 1107-1117
◆Yang, S.H., Lee, D.K., Shin. J., Lee, S., Baek. S., Kim, J., Jung, H., Hah, J.M., and Kim, Y. Nec-1 alleviates cognitive impairment with reduction in Aβ and tau abnormalities in APP/PS1 mice. EMBO. Mol. Med. (2017), 9(1), 61-77
◆Kang, T.B.*, Yang, S.H.*, Toth, B., Kovalenko, A., and Wallach, D. Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. Immunity (2013), 38, 27-40.
◆Rajput, A., Kovalenko, A., Bogdanov, K., Yang, S.H., Kang, T.B., Kim, J.C., Du, J., and Wallach, D. RIG-I RNA Helicase Activation of IRF3 Transcription Factor Is Negatively Regulated by Caspase-8-Mediated Cleavage of the RIP1 Protein. Immunity (2011), 34, 340-351.